Research Article
The Effect of Aloe vera Gel on Widal Titer of Rats Ingested Salmonella typhi Bacteria
@INPROCEEDINGS{10.4108/eai.13-11-2018.2283658, author={Renowati Renowati and Enlita Enlita and Fitra Wahyuni}, title={The Effect of Aloe vera Gel on Widal Titer of Rats Ingested Salmonella typhi Bacteria}, proceedings={Proceedings of the 1st EAI International Conference on Medical And Health Research, ICoMHER November 13-14th 2018, Padang, West Sumatera, Indonesia}, publisher={EAI}, proceedings_a={ICOMHER}, year={2019}, month={5}, keywords={aloe vera gel male white rats salmonella widal agglutination titres}, doi={10.4108/eai.13-11-2018.2283658} }- Renowati Renowati
Enlita Enlita
Fitra Wahyuni
Year: 2019
The Effect of Aloe vera Gel on Widal Titer of Rats Ingested Salmonella typhi Bacteria
ICOMHER
EAI
DOI: 10.4108/eai.13-11-2018.2283658
Abstract
Aloe vera was a traditional medicinal plant that can react as an adjuvant to increase the immune response to antigens because of that Aloe vera was called an immunomodulator. Salmonella typhi bacteria can be destroyed and eliminated by improving macrophage function. This can be done using immunostimulants that have a function as immunomodulators. One plant that acts as an immunostimulant is Aloe vera. The Widal test is one method that utilizes immunology to determine levels of antibodies in the serum, to help diagnose typhoid fever. Based on the description, a study was conducted to see the effect of Aloe vera gel on widal titer in rats that were ingested by Salmonella typhi. This study used white male rats (Rattusnorvegicus L.) strain Wistar, body weight 200 grams consisting of 4 groups with 2 treatments 7 times repetition, namely P1 (Aloe vera gel 1.8 ml/200g/Bw), P2 (Aloe vera gel 3.6 ml/200g/Bw), control (+) ingested Salmonella typhi bacteria and not using Aloe vera gel, (-) using distilled water. The collected data includes objectively tested data, namely Widal titers. The Mann Whitney test results showed that Aloe vera gel affected the decrease of tidal titer (antibodies) in white rats which had been indicated by Salmonella typhimurium bacteria (P <0.05)