Research Article
Study the Extent of The Relationship Among Hormonal Disturbance, Vitamin D Deficiency and Age in Women with Polycystic Ovary Thi-Qar City, Southern Iraq
@INPROCEEDINGS{10.4108/eai.7-9-2021.2315371, author={Shalan H. Al-Saedy and Ali E. Al-Snafi}, title={Study the Extent of The Relationship Among Hormonal Disturbance, Vitamin D Deficiency and Age in Women with Polycystic Ovary Thi-Qar City, Southern Iraq}, proceedings={Proceedings of 2nd International Multi-Disciplinary Conference Theme: Integrated Sciences and Technologies, IMDC-IST 2021, 7-9 September 2021, Sakarya, Turkey}, publisher={EAI}, proceedings_a={IMDC-IST}, year={2022}, month={1}, keywords={hormonal disorders metabolic disorders pcos vitamin d amh}, doi={10.4108/eai.7-9-2021.2315371} }- Shalan H. Al-Saedy
Ali E. Al-Snafi
Year: 2022
Study the Extent of The Relationship Among Hormonal Disturbance, Vitamin D Deficiency and Age in Women with Polycystic Ovary Thi-Qar City, Southern Iraq
IMDC-IST
EAI
DOI: 10.4108/eai.7-9-2021.2315371
Abstract
This study was designed to investigate the relationship between the disturbance of LH, FSH, testosterone, oestradiol, progesterone, and metabolic parameters with AMH, and vitamin D in polycystic ovarian syndrome in a woman. The results showed that in respective to age, PCOS patients showed significant elevation of serum level of LH (P< 0.01), FSH (P< 0.05), LH/FSH ratio (P< 0.05), testosterone (P< 0.01), progesterone (P< 0.05), antimalaria (P< 0.001), glucose (P< 0.01), total cholesterol (P< 0.01), triglycerides (P< 0.001), LDL (P< 0.01), VLDL (P< 0.05) and Vitamin D (P< 0.01), while there were significant decline in the serum level of oestradiol (P< 0.01), and HDL (P< 0.01). It has appeared that AMH was positively correlated with the elevated LH, FSH, LH/FSH ratio, testosterone, progesterone, glucose, total cholesterol, triglycerides, LDL, VLDL levels, and negatively correlated with oestradiol and HDL. While Vitamin D was negatively correlated with AMH. Low serum Vitamin D was associated with elevation of testosterone, LH, FSH, LH/FSH ratio, progesterone, total cholesterol, triglycerides, LDL, and glucose. We can conclude that AMH can potentially be applicate as a diagnostic marker for PCOS, the results also showed a strong correlation between vitamin D deficiency and the pathophysiology of PCOS. Vitamin D serum levels showed an inverse correlation with hyperglycaemia, hyperlipidaemia, and hormonal disturbances in PCOS.