Research Article
Evaluation of Some Biomarkers in the Diagnosis and Severity Identification of Patients with COVID-19
@INPROCEEDINGS{10.4108/eai.7-9-2021.2314940, author={Haider Nasser Jabber and Mahdi Murshid Thuwaini and Hamed Jaddoa Abbas}, title={Evaluation of Some Biomarkers in the Diagnosis and Severity Identification of Patients with COVID-19}, proceedings={Proceedings of 2nd International Multi-Disciplinary Conference Theme: Integrated Sciences and Technologies, IMDC-IST 2021, 7-9 September 2021, Sakarya, Turkey}, publisher={EAI}, proceedings_a={IMDC-IST}, year={2022}, month={1}, keywords={covid-19 sars-cov-2 d-dimer crp ldh}, doi={10.4108/eai.7-9-2021.2314940} }- Haider Nasser Jabber
Mahdi Murshid Thuwaini
Hamed Jaddoa Abbas
Year: 2022
Evaluation of Some Biomarkers in the Diagnosis and Severity Identification of Patients with COVID-19
IMDC-IST
EAI
DOI: 10.4108/eai.7-9-2021.2314940
Abstract
The main purpose of this study, to assess the diagnostic power of the following biomarkers: D dimer, C-reactive protein (CRP), and Lactate Dehydrogenase (LDH) in identifying the diagnosis and severity of COVID-19. A case-control study included (136) patients diagnosed with Covid-19 and (48) healthy subjects as a control group . Kits were also used to measure D dimer, CRP, and LDH. The results of the current study were shown that there was a highly significant increase (P-value < 0.01) in the levels in COVID-19 patients compared to the control group for the biomarkers: D dimer, CRP, and LDH. There was a highly significant increase (P-value < 0.01) in COVID-19 patients with severe disease compared to other groups for the following biomarkers: D dimer and LDH. The study also showed that that the sensitivity values of the markers were 88%, 85%, and 79, for D-dimer, CRP, and LDH, D respectively; while specificity values were: 63%, 61%, and 66% respectively. These markers could be used in the diagnosis of COVID-19.