Research Article
Effect of Parvovirus B19 in Diabetes Mellitus Type 1
@INPROCEEDINGS{10.4108/eai.7-9-2021.2314785, author={Ahmed Hasan Mohammed and Alzahraa Albatool Ibrahim saber}, title={Effect of Parvovirus B19 in Diabetes Mellitus Type 1}, proceedings={Proceedings of 2nd International Multi-Disciplinary Conference Theme: Integrated Sciences and Technologies, IMDC-IST 2021, 7-9 September 2021, Sakarya, Turkey}, publisher={EAI}, proceedings_a={IMDC-IST}, year={2022}, month={1}, keywords={parvovirus b19 type 1 diabetes mellitus pcr fasting blood sugar}, doi={10.4108/eai.7-9-2021.2314785} }- Ahmed Hasan Mohammed
Alzahraa Albatool Ibrahim saber
Year: 2022
Effect of Parvovirus B19 in Diabetes Mellitus Type 1
IMDC-IST
EAI
DOI: 10.4108/eai.7-9-2021.2314785
Abstract
Type 1 diabetes mellitus (T1D) is one of the complicated diseases and many studies indicated the contribution of viruses in the consequences of T1D. The present study aimed to detect of Parvovirus B19 NS1 gene in the sera of T1D patients by using conventional PCR. Forty-five patients with T1D have been conducted in this study based on clinical examination and laboratory evaluation of random blood sugar, fasting blood sugar, and glycated hemoglobin. Viral genome extraction was made according to the kit manufacture’s manual then conventional PCR and gel electrophoresis was performed to detect the target genome. The results showed the presence of NS 1 gene in 7 (14%) of 45 patients included in this study, so conclude that the detection of viral genome in the blood samples of T1D patients is not sufficient to prove that human Parvovirus B19 has a role in the pathogenesis and consequences of T1D.