Proceedings of the First National Seminar Universitas Sari Mulia, NS-UNISM 2019, 23rd November 2019, Banjarmasin, South Kalimantan, Indonesia

Research Article

Effect of HPMC Concentration Variation as Gelling Agent on Physical Stability of Formulation Gel Ethanol Extract Bundung Plants (Actinuscirpus Grossus)

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  • @INPROCEEDINGS{10.4108/eai.23-11-2019.2298326,
        author={Noval  Noval and Rosyifa  Rosyifa and Annisa  Annisa},
        title={Effect of HPMC Concentration Variation as Gelling Agent on Physical Stability of Formulation Gel Ethanol Extract Bundung Plants (Actinuscirpus Grossus)},
        proceedings={Proceedings of the First National Seminar Universitas Sari Mulia, NS-UNISM 2019,  23rd November 2019, Banjarmasin, South Kalimantan, Indonesia},
        publisher={EAI},
        proceedings_a={NS-UNISM},
        year={2020},
        month={7},
        keywords={gel formulation physical stability hpmc ethanol extract of bundung plant},
        doi={10.4108/eai.23-11-2019.2298326}
    }
    
  • Noval Noval
    Rosyifa Rosyifa
    Annisa Annisa
    Year: 2020
    Effect of HPMC Concentration Variation as Gelling Agent on Physical Stability of Formulation Gel Ethanol Extract Bundung Plants (Actinuscirpus Grossus)
    NS-UNISM
    EAI
    DOI: 10.4108/eai.23-11-2019.2298326
Noval Noval1,*, Rosyifa Rosyifa2, Annisa Annisa2
  • 1: Departemen of Pharmacy, Faculty of Health, Universitas Sari Mulia, Banjarmasin, Kalimantan Selatan
  • 2: Pharmacy Department, Health Faculty, Sari Mulia University, Banjarmasin
*Contact email: novalhalim10@gmail.com

Abstract

Bundung Plant is a efficacious as an antimicrobial. In maximizing its use gel formulation are made from ethanol extract of Bundung Plant. The purpose of this study was to know variations in concentrations HPMC as gel agents against the physical stability. Gel formulation was made in 5 formulas with different HPMC concentrations, namely 1% (F1), 1.5% (F2), 2% (F3), 2.5% (F4) & 3% (F5). Gel formulations are result, each evaluated for physical stability including, organoleptic, pH, homogeneity, viscosity and spread ability. The organoleptis testing, pH, homogeneity and viscosity were analyzed descriptively, while spread ability was analyzed statistically linear regression correlation, one-way ANOVA test. The results of the study showed that variations in the concentration of HPMC did not affect odor, shape, color, pH and homogeneity, but have affect viscosity and spread ability on each gel formulation, and all gel formulation are known to be stable during storage