A Review: Protease Inhibitors From Sponge Jaspis Sp. Associated Bacteria

Protease inhibitors are enzymes that function to inactivate target proteases secreted by pathogenic bacteria to humans such as emphysema, pancreatic disease, arthritis, thrombosis, high blood pressure, cancer, and AIDS. The sponge is a good natural source for producing bioactive components including enzyme inhibitors. Jaspis sp is a genus from a sponge that has potential compounds as a protease inhibitor to combat Pseudomonas aeruginosa, Staphylococcus aureus, and EPEC K11. The interaction of sponges with bacteria occurs in the form of commensalism symbiosis that produces bioactive compounds that are important for human life.