Synthesis and Characterization Zn(II)LeucinDithiocarbamate Complex and Their Potential as Anti-Tuberculosis

Desy Kartina; Wahid Wahab; Ahyar Ahmad; Indah Raya; Rizal Irfandi

1st International Conference on Science and Technology, ICOST 2019, 2-3 May, Makassar, Indonesia

Research Article

Synthesis and Characterization Zn(II)LeucinDithiocarbamate Complex and Their Potential as Anti-Tuberculosis

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@INPROCEEDINGS{10.4108/eai.2-5-2019.2284675,
    author={Desy  Kartina and Wahid  Wahab and Ahyar  Ahmad and Indah  Raya and Rizal  Irfandi},
    title={Synthesis and Characterization Zn(II)LeucinDithiocarbamate Complex and Their Potential as Anti-Tuberculosis},
    proceedings={1st International Conference on Science and Technology, ICOST 2019, 2-3 May, Makassar, Indonesia},
    publisher={EAI},
    proceedings_a={ICOST},
    year={2019},
    month={6},
    keywords={dithiocarbamate in situ method anti-tuberculosis complexes},
    doi={10.4108/eai.2-5-2019.2284675}
}

Desy Kartina
Wahid Wahab
Ahyar Ahmad
Indah Raya
Rizal Irfandi
Year: 2019
Synthesis and Characterization Zn(II)LeucinDithiocarbamate Complex and Their Potential as Anti-Tuberculosis
ICOST
EAI
DOI: 10.4108/eai.2-5-2019.2284675

Desy Kartina¹^,*, Wahid Wahab¹, Ahyar Ahmad¹, Indah Raya¹, Rizal Irfandi¹

1: Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Hasanuddin, Indonesia. 90245

*Contact email: desy.kartina@yahoo.com

Abstract

Metal-dithiocarbamate complexes find wide-ranging applications in nanomaterial and have potential use as chemotherapeutic and antibacterial. New complexes of Zn(II)LeucineDithiocarbamate have been synthesized using an “in situ” method from reactions of Leucine Dithiocarbamate in mole ratios 1:2 giving the result of around 45,44% and characterized with the instrument of FTIR (Fourier Transform Infra Red), UV-Vis (Ultra Violet Visible), melting point and conductometry. These complex indicate bioactivity more potentials against Mycobacterium tuberculosis as compared to the free ligand with using the LJ method. Therefore, this complex could be used to develop as a new compound in the treatment of tuberculosis

Keywords: dithiocarbamate in situ method anti-tuberculosis complexes

Published: 2019-06-14
Publisher: EAI

: http://dx.doi.org/10.4108/eai.2-5-2019.2284675