Proceedings of the 1st EAI International Conference on Medical And Health Research, ICoMHER November 13-14th 2018, Padang, West Sumatera, Indonesia

Research Article

Comparison of Risk Factors Related to Survival in Breast Cancer Patients in The Low and High Plains in West Sumatra, Indonesia

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  • @INPROCEEDINGS{10.4108/eai.13-11-2018.2283663,
        author={Rima  Semiarty and Rosfita  Rasyid and Daan  Khambri and Ricvan Dana Nindrea and Cimi  Ilmiawati},
        title={Comparison of Risk Factors Related to Survival in Breast Cancer Patients in The Low and High Plains in West Sumatra, Indonesia},
        proceedings={Proceedings of the 1st EAI International Conference on Medical And Health Research, ICoMHER November 13-14th 2018, Padang, West Sumatera, Indonesia},
        publisher={EAI},
        proceedings_a={ICOMHER},
        year={2019},
        month={5},
        keywords={breast cancer risk factor low-high plains},
        doi={10.4108/eai.13-11-2018.2283663}
    }
    
  • Rima Semiarty
    Rosfita Rasyid
    Daan Khambri
    Ricvan Dana Nindrea
    Cimi Ilmiawati
    Year: 2019
    Comparison of Risk Factors Related to Survival in Breast Cancer Patients in The Low and High Plains in West Sumatra, Indonesia
    ICOMHER
    EAI
    DOI: 10.4108/eai.13-11-2018.2283663
Rima Semiarty1,*, Rosfita Rasyid1, Daan Khambri2, Ricvan Dana Nindrea1, Cimi Ilmiawati3
  • 1: Department of Public Health and Community Medicine, Faculty of Medicine Universitas Andalas, Padang, Indonesia
  • 2: Department of Surgical Oncology, Faculty of Medicine Universitas Andalas, Padang, Indonesia
  • 3: Department of Environmental and Preventive Medicine, Jichi Medical School of Medicine, Japan
*Contact email: rimamenkher@yahoo.com

Abstract

Breast cancer continues to be a major cause of morbidity among women in Indonesia. This study was designed to explore the comparison of risk factor related to survival in breast cancer patients in the low and high plains in West Sumatera, Indonesia. Data were extracted from medical records of Dr M Djamil General Hospital Padang in 2007 until 2016 for all breast cancer patients treated with a 219 patients. Disease free survival and overall survival rates and their relationship with low and high plains residence were investigated using survival analysis and risk factors related to survival in breast cancer patients using chi-square test. Disease free survival in breast cancer patients in the low plains was 54 months (95% CI 45-63) lower than high plains 63 months (95% CI 54-72). Overall survival rate revealed median survival of 57 months (95% CI 49-64) in low plains lower than high plains 62 months (95% CI 53-72). Stage had the highest hazard ratio or dominant factor for breast cancer patients in low plains (HR = 7.9 [95% CI=3.42-18.34]) and high plains (HR= 6.3 [95% CI = 1.12-34.73]). This analysis confirmed breast cancer patients in the low plains had low survival rate than high plains. Advance stage, obesity and family history of breast cancer associated with survival in breast cancer patients in low plains but in high plains residence are advance stage, low-level education, work, and obesity. The stage had the highest hazard ratio for breast cancer