Research Article
Anticancer Activity of Silver Nan Particles against Cell Line MCF-7–Human - Breast Cancer through MTT Assay
@INPROCEEDINGS{10.4108/eai.7-12-2021.2314712, author={C. K. Senthilkumaran and S. Sugapriya}, title={Anticancer Activity of Silver Nan Particles against Cell Line MCF-7--Human - Breast Cancer through MTT Assay}, proceedings={Proceedings of the First International Conference on Combinatorial and Optimization, ICCAP 2021, December 7-8 2021, Chennai, India}, publisher={EAI}, proceedings_a={ICCAP}, year={2021}, month={12}, keywords={silver nanoparticles cytotoxicity mcf-7 and mtt assay}, doi={10.4108/eai.7-12-2021.2314712} }- C. K. Senthilkumaran
S. Sugapriya
Year: 2021
Anticancer Activity of Silver Nan Particles against Cell Line MCF-7–Human - Breast Cancer through MTT Assay
ICCAP
EAI
DOI: 10.4108/eai.7-12-2021.2314712
Abstract
Silver nanoparticles were synthesized by simple chemical precipitation method demonstrated a considerable activity of anticancer against cell line MCF 7human - breast cancer at variousdoses. Above 60 % of cell death has been observed in maximum concentration level of 1000 µL. Results showed that at higher concentration levels have significant cell mortality. After the 48 hours of incubation the inhibitory effect was observed. Consequently, 50%onkilling the cancer cell decides the Inhibitory. Concentration I,C50of the prepared silver nanoparticles in case of cell lineMCF-7human breast cancer, holds at round 846 µL. In addition, the light microscopic observation of control and different concentration of silver nanoparticles sample treated cell lines MCF-7 was studied.